基本信息
刘美玲,理学博士,教授,博士生导师,湖南省芙蓉学者青年学者,湖南省芙蓉百岗明星获得者,湖南省青年骨干教师培养对象。2006年硕士毕业留校工作,2012年获得理学博士学位。2017年6月-2018年6月在加州大学洛杉矶分校访学。主要从事生物药物分析、化学生物传感及诊疗应用等领域的研究工作。曾获湖南省自然科学奖二等奖、湖南省优秀博士论文和湖南省优秀硕士论文奖等奖项。主持和完成4项国家自然科学基金、多项湖南省科技厅、教育厅及企业合作课题。在Adv. Mater., Sci. China Chem., Angew. Chem. Int. Ed., Anal. Chem.等国内外刊物发表论文150余篇,被Chem. Rev等SCI期刊他引7100多次,H-index 47,多篇论文进入高被引行列。
邮箱:liuml@hunnu.edu.cn; liumeilingww@126.com
研究兴趣及方向
1)纳米材料的表面调控及生物传感研究;
2)零维纳米点及量子点的制备与催化应用;
3)新型光电功能材料的制备与应用。
科研项目
1. 过渡金属氧化物纳米酶多功能反应器调控、监测H2O2/GSH水平及级联催化治疗初探,2023.01~2026.12,国家自然科学基金,54万,在研。
2. 酶解产香技术在天然香料开发中的研究与应用(植物源增香酶筛选及研究),2014.07 ~2026.5,云南中烟工业有限责任公司,35万,在研。
3. 基于单原子纳米酶催化的诊疗平台的设计与应用研究,88805j新莆京芙蓉学者科研经费,25万,在研。
3. 多功能“智能纳米卷”的制备及其在癌症诊断、监测与治疗中的应用,2020.01~2023.12,国家自然科学基金,63万,已结题。
4. 基于碳点和新型植物提取物制备的双金属纳米材料及应用,2017.01~2017.12,国家自然科学基金,10万,已结题。
5. 基于新型二茂铁衍生物/功能化石墨烯纳米材料修饰电极的电化学传感研究,2013.01 ~2016.12,国家自然科学基金青年基金,25万,已结题。
6. 基于过渡金属氧化物多纳米酶性质的癌症诊断和治疗体系的构建与应用,湖南省自然科学基金,10万,已结题。
7. 二维多孔纳米片/金属纳米簇多功能纳米复合物的制备及其在生化分析与疾病诊断中的应用,2019.01~2021.12,湖南省教育厅优秀青年基金,6万,已结题。
8. 科研驱动本科拔尖创新人才培养的探索与实践,湖南省教学改革课题,2万,已结题。
主要发表的论文
2025年
1. Liu, J.; Wang, M.; Yang, X.; Chen, H.; Liu, M.;* Zhu, X.; Zhang, Y.; Liu, M.;* Yao, S. Covalent conjugation of doxorubicin to polydopamine on the surface of single-atom nanozyme for effective synergistic cancer therapy. Science China-Chemistry 2025, DOI:10.1007/s11426-024-2592-4 10.1007/s11426-024-2592-4.
2. Chen, H.; Wang, M.; Yang, Q.; Liu, J.; Liu, F.; Zhu, X.; Huang, S.; Yin, P.; Wang, X.; Li, H. Liu, M.;* et al. Multifunctional porphyrinic metal-organic framework-based nanoplatform regulating reactive oxygen species achieves efficient imaging-guided cascaded nanocatalytic therapy. Journal of Colloid and Interface Science 2025, 684, 423.
3. Chen, H.; Liu, R.; Fu, J.; Zhang, X.; Zhu, X.; Wei, M.;* Liu, F.; Yin, P.; Li, H.; Zhang, Y.; Liu, M.;* Liu, J. Surface engineering of copper peroxide nanodots and Au nanozyme on porphyrin-based metal-organic frameworks induces cascade reactions for colorectal cancer treatment. Chemical Engineering Journal 518 (2025) 164764.
4. Liu, X.; Chen, H.; Hu, X.; Liu, J.; Zhu, X.; Zhang, Y.; Liu, M.; * CN- as a cofactor enhancing the laccase-like activity of copper porphyrin metal-organic frameworks facilitates the sensitive cyanide detection. Sensors & Actuators: B. Chemical 2025, 442, 138135.
5. Liu, Y.; Chen, H.; Chai, L.; Liu, J.; Huang, S.; Liu, F.; Zhu, X.; Zhang, Y.; Liu, M.;* Yao, S. Total antioxidant capacity assessment and accurate quantification of ascorbic acid and glutathione utilizing the enhanced multi-mimetic of Cu-CeO2 NPs decorated PCN-224. Sensors and Actuators B-Chemical 2025, 437, 137709.
6. Tan, H.; Zeng, M.; Fang, C.; Zhu, X.; Liu, F.; Long, Y.; Deng, R.; Yin, P.; Liu, M.;* Li, H.et al. Pattern-based rapid and robust profiling of gut microbiota and its metabolism with a single fluorescent probe. Science China-Chemistry 2025, 68 (2), 781.
7. Chen, H.; Chai, L.; Gui, J.; Liu, Y.; Liu, M.; * Liu, X*; Zhang, Y.; Yao, S. Copper-manganese bimetallic oxide with excellent laccase-like activity for colorimetric detection of formaldehyde via the specific aldimine condensation reaction. Talanta 2025, 293, 128151.
8. Li, W.; Zhong, Y.; Zhou, P.; Li, P.; Huang, S.; Zhu, X.; Zhang, Y.; Liu, M.; * Yao, S. Dual-functional silver-based metal-organic frameworks facilitate electrochemical/ electrochemiluminescent dual-channel detection of chloride ions and glutathione. Talanta 2025, 294, 128278.
9. Zhou, J.; Zhao, L.; Zhong, Y.; Li, P.; Zhu, X.; Huang, S.; Zhang, Y.; Liu, M.* Dual-mode detection of human immunoglobulin via copper oxide nanozyme catalysis fluorescent species generation and photoelectrochemical alteration in ZnIn2S4/SnO2-based system. Analytica Chimica Acta 2025, 1333.
2024 年
1. Gui, J.; Fan, Y.; Chen, H.; Liu, F.; Huang, S.; * Wei, M.; Zhu, X.; Zhang, Y.; Liu, M.; * Yao, S. Redox-induced multisignal sensing based on fluorescent polydopamine nanoparticles and MnO2 nanozyme for the detection and differentiation of reducing substances. ACS Applied Nano Materials 2024, 7 (14), 16320.
2. Li, W.; Liu, J.; Zhong, Y.; Li, P.; Zhu, X.; Zhang, Y.; Liu, M.; * Yao, S. Single-atom iron nanoatalysts facilitate electrochemiluminescence of graphitic carbon nitride for copper ion sensing. Sensors and Actuators B-Chemical 2024, 417.
3. Liu, X.; Chen, H.; Hu, X.; Liu, J.; Zhong, Y.; Li, P.; Zhu, X.; Zhang, Y.; Liu, M.;* Yao, S. Traffic lights inspired colorimetric sensing platform for cadmium/lead ions: PO43- induced structural change of porphyrin metal-organic framework. Sensors and Actuators B-Chemical 2024, 420.
4. Liu, Y.; Chen, H.; Chai, L.; Liu, J.; Huang, S.; Liu, F.; Wei, M.; Zhu, X.; Zhang, Y.; Liu, M*. et al. A dual-channel sensing platform for ATP and copper ions via the target-induced peroxidase mimics activity and fluorescence variations of iron oxide nanoparticles-modified metal-organic frameworks. Sensors and Actuators B-Chemical 2024, 418.
5. Zhao, L.; Zhou, J.; Li, P.; Huang, S.; Zhu, X.; Zhang, Y.; Liu, M.; * Yao, S. Target-induced photoelectrochemistry and colorimetric dual-mode platform for HIgG based on Ag2S/SnO2 composites and CoOOH nanoflakes. Sensors and Actuators B-Chemical 2024, 409.
6. Lili Zhao, Haoyu Chen, Jiawei Zhou, Peipei Li, Wenying Zhao,* Xiaohua Zhu, Youyu Zhang, and Meiling Liu*; Alkaline phosphatase-decorated Au nanoparticles immobilized on Bi2S3 particles combined with Ag2S quantum dots as a photoelectrochemical sensing platform for alkaline phosphatase activity and fluoride ions. ACS Appl. Nano Mater. 2024, 7, 5252-5262. ( https://doi.org/10.1021/acsanm.3c05917)
7. Lili Zhao, Jiawei Zhou, Peipei Li, Shu Huang*, Xiaohua Zhu, Youyu Zhang, Meiling Liu*, Shouzhuo Yao. Target-induced photoelectrochemistry and colorimetric dual-mode platform for HIgG based on Ag2S/SnO2 composites and CoOOH nanoflakes, Sensors & Actuators: B. Chemical 409 (2024) 135638. (https://doi.org/10.1016/j.snb.2024.135638)
8. Wenjie Li, Zhenjuan Xu, Peipei Li, Xiang Liu, Chao Chen, Youyu Zhang, Meiling Liu,* Shouzhuo Yao. A sensitive electrochemical sensor for glutathione based on specific recognition induced collapse of silver-contained metal organic frameworks, Microchimica Acta (2024) 191:49 (https://doi.org/10.1007/s00604-023-06152-9)
9. 高洁, 廖俊宇, 朱效华*, 刘美玲*, 张友玉, 姚守拙, 荧光碳点基多通道传感器阵列快速鉴别金属离子,中国科学: 化学, SSC-2023-0254.
10. Luo, L.; Liu, J.; Liu, Y.; Chen, H.; Zhang, Y.; Liu, M.*; Yao, S. In situ formation of fluorescence species for the detection of alkaline phosphatase and organophosphorus pesticide via the ascorbate oxidase mimetic activity of AgPd bimetallic nanoflowers. Food Chemistry 2024, 430,137062. (10.1016/j.foodchem.2023.137062)
11. Liu, J.; Zhu, Y.; Fan, Y.; Gong, L.; Zhu, X.; Zhang, Y.; Liu, M.*; Yao, S. The pH-dependent multiple nanozyme activities of copper-cerium dioxide and its application in regulating intracellular oxygen and hydrogen peroxide levels. Journal of Colloid and Interface Science 2024, 654, 1054. (10.1016.j.jcis.2023.10.050).
12. Fang, C.; Deng, Q.; Zhao, K.; Zhou, Z.; Zhu, X.; Liu, F.; Yin, P.; Liu, M.; Li, H.; Zhang, Y.et al. Fluorescent Probe for Investigating the Mitochondrial Viscosity and Hydrogen Peroxide Changes in Cerebral Ischemia/Reperfusion Injury. Analytical Chemistry 2024, 96 (8), 3436.
13. Gao, J.; Zhu, X.; Long, Y.; Liu, M.; Li, H.; Zhang, Y.; Yao, S. Boronic Acid-Decorated Carbon Dot-Based Semiselective Multichannel Sensor Array for Cytokine Discrimination and Oral Cancer Diagnosis. Analytical Chemistry 2024, 96 (4), 1795.
14. Zhu, X.; Chen, J.; Liao, J.; Wang, M.; Long, Y.; Liu, M.; Zhang, Y.; Wang, H.-H. Functionalized multichannel fluorescence-encoded nanosystem on erythrocyte-coated nanoparticles for precise cancer subtype discrimination. Nano Letters 2024, 25 (1), 426.
2023年
1. Li, R.; Zhu, Y.; Gong, L.; Fan, Y.; Zhang, J.; Wu, S.; Luo, K.; Zhu, X.*; Liu, M.*; Zhang, Y.et al. Synthesis and catalytic performance of Cu-CeO2 nanoparticles and the application in Cr (VI) detection: third-year undergraduate comprehensive laboratory experiment. Journal of Chemical Education 2023, 100 (10), 3945. (10.1021/acs.jchemed.3c00548)
2. Gui, J.; Chen, H.; Liu, J.; Liu, Y.; Wu, C.; Zhu, X.; Wei, M.*; Liu, M.*; Zhang, Y.; Yao, S. Consuming intracellular glucose and regulating the levels of O2/H2O2 via the closed cascade catalysis system of Cu-CeO2 nanozyme and glucose oxidase. Journal of Colloid and Interface Science 2023, 651, 191. (10.1016/j.jcis.2023.07.190)
3. Chen, H.; Tang, Y.; Gui, J.; Li, P.; Zhu, X.; Wu, C.; Yin, P.; Liu, M.*; Zhang, Y.; Yao, S. Detection and bioimaging of glutathione in cells via a turn-on near-infrared fluorescent nanoprobe composed of Ag2S quantum dots and CoOOH nanosheets. ACS Applied Nano Materials 2023, 6(3), 1870. (10.1021/acsanm.2c04853)
4. Liu, J.; Gong, L.; Chen, H.; Gui, J.; Zhu, X.; Liu, M.*; Zhang, Y.; Yao, S. Fe-single-atom nanozyme catalysts for sensitive and selective detection of nitrite via colorimetry and test strips. ACS Applied Nano Materials 2023, 6 (7), 5879. (10.1021/acsanm.3c00253)
5. Chen, H.; Cai, Z.; Gui, J.; Tang, Y.; Yin, P.; Zhu, X.; Zhang, Y.; Li, H.; Liu, M.*; Yao, S. A redox reaction-induced ratiometric fluorescence platform for the specific detection of ascorbic acid based on Ag2S quantum dots and multifunctional CoOOH nanoflakes. Journal of Materials Chemistry B 2023, 11 (6), 1279. (10.1039/d2tb02438a)
6. Luo, L.; Li, P.; Liu, X.; Zeng, W.; Zhang, Y.; Liu, M.*; Yao, S. Synthesis of carbon-based Ag-Pd bimetallic nanocomposite and the application in electroless copper deposition. Electrochimica Acta 2023, 439, 141679. (10.1016/j.electacta.2022.141679)
7. Zhu, Y.; Liu, J.; Liu, Y.; Wu, C.; Zhu, X.; Zhang, Y.; Liu, M.*; Yao, S. Self-supplying of hydrogen peroxide/oxygen based on CaO2-Co3O4 cascade nanoreactors for cellular microenvironment regulation. ACS Applied Nano Materials 2023, 6 (14), 12904. (10.1021/acsanm.3c01642)
8. Zhang, J.; Chen, H.; Liu, J.; Gui, J.; Liu, M.*; Zhang, Y.; Yao, S. The target-induced redox and diazotized reaction for colorimetric ratio detection of nitrite using CoOOH nanosheets as mimetic oxidase. Talanta 2023, 258, 124458. (10.1016/j.talanta.2023. 124458)
9. Zhao, L.; Chen, H.; Tang, Y.; Li, P.; Zhu, X.; Liu, J.; Liu, M.*; Zhang, Y.; Yao, S. Ag2S QDs integration with MnO2 nanosheets for the sensitive detection of Cr (VI) via the redox reaction induced photoelectrochemical variation. Analytica Chimica Acta 2023, 1270, 341471. (10.1016/j.aca.2023.341471)
10. Liu, Z.; Zhu, X.; Lu, Q.; Liu, M.; Li, H.; Zhang, Y.; Liu, Y.; Yao, S. Recognition engineering-mediated multichannel sensor array for gut microbiota sensing. Analytical Chemistry 2023, 95 (14), 5911.
2022年
1. Li, P.; Luo, L.; Cheng, D.; Sun, Y.; Zhang, Y.; Liu, M.*; Yao, S. Regulation of the structure of zirconium-based porphyrinic metal-organic framework as highly electrochemiluminescence sensing platform for thrombin. Analytical Chemistry 2022, 94 (14), 5707. (10.1021/acs.analchem.2c00737)
2) Xu, Y.; Yan, J.; Zhu, Y.; Chen, H.; Wu, C.; Zhu, X.; Zhang, Y.; Li, H.; Liu, M.*; Yao, S. Self-cascade nanoenzyme of cupric oxide nanoparticles (CuO NPs) induced in situ catalysis formation of polyelectrolyte as template for the synthesis of near-infrared fluorescent silver nanoclusters and the application in glutathione detection and bioimaging. Analytical Chemistry 2022, 94 (42), 14642. (10.1021/acs.analchem.2c02832)
(3) Cheng, D.; Li, P.; Xu, Z.; Liu, X.; Zhang, Y.; Liu, M.*; Yao, S. Signal on-off electrochemical sensor for glutathione based on a AuCu-decorated Zr-containing metal-organic framework via solid-state electrochemistry of cuprous chloride. ACS Sensors 2022, 7 (8), 2465. (10.1021/acssensors.2c01221)
(4) Li, P.; Xu, Z.; Zhao, L.; Chen, H.; Zhu, X.; Zhang, Y.; Liu, M.*; Yao, S. Nanoluminophores composed of 1,1'-ferrocenedicarboxylic acid and tetrakis-(4-carboxyphenyl) porphyrin for electrochemiluminescence sensing. ACS Applied Nano Materials 2022, 5 (11), 16278. (10.1021/acsanm.2c03327)
(5) Zhu, Y.; Yan, J.; Liu, J.; Chen, H.; Gui, J.; Wu, C.; Zhu, X.; Yin, P.; Liu, M.*; Zhang, Y.et al. Multi-mimic activities of Co3O4 nanopolyhedrons and application in regulating the content of intracellular hydrogen peroxide/oxygen. ACS Applied Nano Materials 2022, 5(10),15102-15114. (10.1021/acsanm.2c03271)
(6) Xu, Z.; Li, P.; Chen, H.; Zhu, X.; Zhang, Y.; Liu, M.*; Yao, S. Picomolar glutathione detection based on the dual-signal self-calibration electrochemical sensor of ferrocene-functionalized copper metal-organic framework via solid-state electrochemistry of cuprous chloride. Journal of Colloid and Interface Science 2022, 628, 798. (10.1016/j.jcis.2022.08.107)
(7) Cheng, D.; Liu, X.; Li, P.; Zhang, Y.; Liu, M.*; Yao, S. Novel ratiometric electrochemical sensing platform for uric acid based on electroactive cuprous oxide nanocubes combined with boron carbide. Analyst 2022, 147 (21), 4777-4785. (10.1039/d2an01270g)
(8) Xu, Z.; Li, P.; Liu, X.; Zhu, X.; Liu, M.*; Zhang, Y.; Yao, S. Dual-signal intrinsic self-calibration ratio electrochemical sensor for glutathione based on silver nanoparticle decorated Prussian Blue analog. Electrochimica Acta 2022, 434, 141273. (10.1016/j.electacta.2022.141273)
(9) Xu, Y.; Li, P.; Zhu, Y.; Tang, Y.; Chen, H.; Zhu, X.; Wu, C.; Zhang, Y.; Liu, M.*; Yao, S. A fluorescence nanoplatform for the determination of hydrogen peroxide and adenosine triphosphate via tuning of the peroxidase-like activity of CuO nanoparticle decorated UiO-66. Microchimica Acta 2022, 189 (3), 119. (10.1007/s00604-022-05170-3)
(10) Liu, Q.; Lin, Y.; Yue, L.; Liang, J.; Zhang, L.; Li, T.; Luo, Y.; Liu, M.*; You, J.; Alshehri, A. A.et al. Bi nanoparticles/carbon nanosheet composite: A high-efficiency electrocatalyst for NO reduction to NH3. Nano Research 2022, 15 (6), 5032. (10.1007/s12274-022-4283-9)
(11) Zhang, L.; Wang, J.; Liu, P.; Liang, J.; Luo, Y.; Cui, G.; Tang, B.; Liu, Q.; Yan, X.; Hao, H.; Liu, M.* et al. Ni(OH)2 nanoparticles encapsulated in conductive nanowire array for high-performance alkaline seawater oxidation. Nano Research 2022, 15 (7), 6084. (10.1007/s12274-022-4391-6)
2021年
1. Ma, Z.; Xu, Y.; Li, P.; Cheng, D.; Zhu, X.; Liu, M.*; Zhang, Y.; Liu, Y.; Yao, S. Self-catalyzed surface reaction-induced fluorescence resonance energy transfer on cysteine-stabilized MnO2 quantum dots for selective detection of dopamine. Analytical Chemistry 2021, 93 (7), 3586. (10.1021/acs.analchem.0c05102)
2. Zhao, Q.; Shen, T.; Liu, Y.; Hu, X.; Zhao, W.; Ma, Z.; Li, P.; Zhu, X.; Zhang, Y.; Liu, M.*; Universal nanoplatform for formaldehyde detection based on the oxidase-mimicking activity of MnO2 nanosheets and the in situ catalysis-produced fluorescence species. Journal of Agricultural and Food Chemistry 2021, 69 (26), 7303. (10.1021/acs.jafc.1c01174)
3. Zhu, X.; Zhang, Y.; Liu, M.*; Liu, Y. 2D Titanium carbide MXenes as emerging optical biosensing platforms. Biosensors & Bioelectronics 2021, 171, 112730. (10.1016/j.bios.2020.112730)
4. Sun, Y.; Li, P.; Zhu, Y.; Zhu, X.; Zhang, Y.; Liu, M.*; Liu, Y*. In situ growth of TiO2 nanowires on Ti3C2 MXenes nanosheets as highly sensitive luminol electrochemiluminescent nanoplatform for glucose detection in fruits, sweat and serum samples. Biosensors & Bioelectronics 2021, 194. (10.1016/j.bios.2021.113600)
5. Qiu, L.; Ma, Z.; Li, P.; Hu, X.; Chen, C*.; Zhu, X.; Liu, M.*; Zhang, Y.; Li, H.; Yao, S. Sensitive and selective detection of chromium (VI) based on two-dimensional luminescence metal organic framework nanosheets via the mechanism integrating chemical oxidation-reduction and inner filter effect. Journal of Hazardous Materials 2021, 419, 126443. (10.1016/j.jhazmat.2021.126443)
6. Xie, J.; Cheng, D.; Li, P.; Xu, Z.; Zhu, X.*; Zhang, Y.; Li, H.; Liu, X.; Liu, M.*; Yao, S. Au/metal-organic framework nanocapsules for electrochemical determination of glutathione. ACS Applied Nano Materials 2021, 4 (5), 4853. (10.1021/acsanm.1c00394)
7. Xu, Y.; Li, P.; Hu, X.; Chen, H.; Tang, Y.; Zhu, Y.; Zhu, X.*; Zhang, Y.; Liu, M.*; Yao, S. Polyoxometalate nanostructures decorated with Cuo nanoparticles for sensing ascorbic acid and Fe2+ ions. ACS Applied Nano Materials 2021, 4 (8), 8302. (10.1021/acsanm.1c01495)
8. Cheng, D.; Li, P.; Zhu, X.; Liu, M.*; Zhang, Y.; Liu, Y. Enzyme-free electrochemical detection of hydrogen peroxide based on the three-dimensional flower-like cu-based metal organic frameworks and MXene nanosheets(dagger). Chinese Journal of Chemistry 2021, 39 (8), 2181. (DOI: 10.1002/cjoc.202100158)
9. Li, P.; Cheng, D.; Zhu, X.; Liu, M.; Zhang, Y. Partial oxidation of MnS for Synergistic electrocatalysis of N2-to-NH3 fixation at ambient conditions,Journal of the Electrochemical Society, 2021, 168,116518. (1945-7111/2021/168(11)/116518/6)
2020 年
1. Sun, Y.; Zhang, Y.; Zhang, H.; Liu, M.*; Liu, Y. *, Integrating highly efficient recognition and signal transition of g-C3N4 embellished Ti3C2 MXene hybrid nanosheets for electrogenerated chemiluminescence analysis of protein kinase activity. Analytical Chemistry 2020, 92 (15), 10668-10676.
2. Ma, Z.; Sun, Y.; Xie, J.; Li, P.; Lu, Q.; Liu, M.*; Yin, P.; Li, H.; Zhang, Y.; Yao, S., Facile preparation of MnO2 quantum dots with enhanced fluorescence via microenvironment engineering with the assistance of some reductive biomolecules. ACS Applied Materials & Interfaces 2020, 12 (13), 15919-15927.
3. Cao, Y.; Li, P.; Wu, T.; Liu, M.*; Zhang, Y., Electrocatalysis of N2 to NH3 by HKUST-1 with high NH3 Yield. Chemistry-an Asian Journal 2020, 15 (8), 1272-1276.
4. Xie, J.; Cheng, D.; Zhou, Z.; Pang, X.; Liu, M.*; Yin, P.; Zhang, Y.; Li, H.; Liu, X.; Yao, S., Hydrogen peroxide sensing in body fluids and tumor cells via in situ produced redox couples on two-dimensional holey CuCo2O4 nanosheets. Microchimica Acta 2020, 187 (8).
5. Zhang, Q.; Sun, Y.; Liu, M.*; Liu, Y., Selective detection of Fe3+ ions based on fluorescence MXene quantum dots via a mechanism integrating electron transfer and inner filter effect. Nanoscale 2020, 12 (3), 1826-1832.
6. Li, P.; Wu, C.; Cheng, D.; Lu, Q.; Gao, J.; Yang, Y.; Zhu, X.; Liu, M.;* Li, H.; Yin, P.; Zhang Y. *; Group IV nanodots: Newly emerging properties and application in biomarkers sensing, Trends in Analytical Chemistry 2020, 131, 116007.
7. Xu, Y.; Li, P.; Wu, C.; Cheng, D.; Lu, Q.; Gao, J.; Yang, Y.; Zhu, X.; Liu, M.;* Li, H.; Yin, P.; Zhang Y. *; Group IV nanodots: synthesis, surface engineering and application in bioimaging and biotherapy, Journal of Materials Chemistry B, 2020, 8, 10290
2019 年
1. Liu, M. #; Zhao, Z.#; Duan, X.*, Huang, Y.*. Nanoscale Structure Design for High-Performance Pt-Based ORR Catalysts. Advanced Materials 2019, 31 (6).
2. Wu, T.; Li, P.; Wang, H.; Zhao, R.; Zhou, Q.; Kong, W.; Liu, M.;* Zhang, Y.; Sun, X.;* Gong, F., Biomass-derived oxygen-doped hollow carbon microtubes for electrocatalytic N2-to-NH3 fixation under ambient conditions. Chemical Communications 2019, 55 (18), 2684-2687.
3. Li, P.; Wang, J.; Chen, H.; Sun, X.; You, J.; Liu, S.; Zhang, Y.; Liu, M.;* Niu, X.; Luo, Y.*, Synergistic electrocatalytic N2 reduction using a PTCA nanorod-rGO hybrid. Journal of Materials Chemistry A 2019, 7 (20), 12446-12450.
4. Li, P.; Liu, Z.; Wu, T.; Zhang, Y.; Wang, L.; Wang, L.; Ji, L.; Zhang, Y.; Luo, Y.; Wang, T.; Liu, S.; Wu, Y.; Liu, M.;* Sun, X.*, Ambient electrocatalytic N2 reduction to NH3 by metal fluorides. Journal of Materials Chemistry A 2019, 7 (30), 17761-17765.
5. Li, P.; Zhao, R.; Chen, H.; Wang, H.; Wei, P.; Huang, H.; Liu, Q.; Li, T.; Shi, X.; Zhang, Y.; Liu, M.; Sun, X., Recent advances in the development of water oxidation electrocatalysts at mild pH. Small 2019, 15 (13).
6. Wu, T.; Ma, Z.; Li, P.; Lu, Q.; Liu, M.;* Li, H.; Zhang, Y.; Yao, S., Bifunctional colorimetric biosensors via regulation of the dual nanoenzyme activity of carbonized FeCo-ZIF. Sensors and Actuators B-Chemical 2019, 290, 357-363.
7. Mo, F.; Ma, Z.; Wu, T.; Liu, M.;* Zhang, Y.; Li, H.; Yao, S., Holey reduced graphene oxide inducing sensitivity enhanced detection nanoplatform for cadmium ions based on glutathione-gold nanocluster. Sensors and Actuators B-Chemical 2019, 281, 486-492.
8. Mo, F.; Xie, J.; Wu, T.; Liu, M.;* Zhang, Y.; Yao, S., A sensitive electrochemical sensor for bisphenol A on the basis of the AuPd incorporated carboxylic multi-walled carbon nanotubes. Food Chemistry 2019, 292, 253-259.
9. Wu, T.; Hou, W.; Ma, Z.; Liu, M.;* Liu, X.; Zhang, Y.; Yao, S., Colorimetric determination of ascorbic acid and the activity of alkaline phosphatase based on the inhibition of the peroxidase-like activity of citric acid-capped Prussian Blue nanocubes. Microchimica Acta 2019, 186 (2).
10. Ma, Z.; Wu, T.; Li, P.; Liu, M.;* Huang, S.; Li, H.; Zhang, Y.; Yao, S., A dual (colorimetric and fluorometric) detection scheme for glutathione and silver (I) based on the oxidase mimicking activity of MnO2 nanosheets. Microchimica Acta 2019, 186 (8).
11. Yao, J.; Wu, T.; Sun, Y.; Ma, Z.; Liu, M.;* Zhang, Y.; Yao, S., A novel biomimetic nanoenzyme based on ferrocene derivative polymer NPs coated with polydopamine. Talanta 2019, 195, 265-271.
12. Wu, T.; Ma, Z.; Li, P.; Liu, M.;* Liu, X.; Li, H.; Zhang, Y.; Yao, S., Colorimetric detection of ascorbic acid and alkaline phosphatase activity based on the novel oxidase mimetic of Fe-Co bimetallic alloy encapsulated porous carbon nanocages. Talanta 2019, 202, 354-361.
2018年
1. Zhang, Q.; Wang, F.; Zhang, H.; Zhang, Y.; Liu, M.*; Liu, Y.* Universal Ti3C2 MXenes based self-standard ratiometric fluorescence resonance energy transfer platform for highly sensitive detection of exosomes. Analytical Chemistry 2018, 90(21): 12737-12744.
2. Chen, Y.; Liu, X.; Wu, T.; Hou, W.; Liu, M.*; Zhang, Y.; Yao, S. Enhanced electrochemical sensitivity towards acetaminophen determination using electroactive self-assembled ferrocene derivative polymer nanospheres with multi-walled carbon nanotubes. Electrochimica Acta, 2018, 272: 212-220.
3. Hou, W.; Liu, X.; Lu, Q.; Liu, M.*; Zhang, Y.; Yao, S. Etching and anti-etching strategy for sensitive colorimetric sensing of H2O2 and biothiols based on silver/carbon nanomaterial, Colloids and Surfaces B: Biointerfaces, 2018, 162, 118-125.
4. Hou, W.; Chen, Y.; Lu, Q.; Liu, M.*; Zhang, Y.; Yao, S. Silver ions enhanced AuNCs fluorescence as a turn-off nanoprobe for ultrasensitive detection of iodide, Talanta, 2018, 162, 118-125.
5. Miao, Z.; Hou, W.; Liu, M.; *, Zhang, Y.; Yao, S. BSA capped bi-functional fluorescent Cu nanoclusters as pH sensor and selective detection of dopamine. New Journal of Chemistry, 2018, 42,1446-1456.
6. Chen, H.; Lu, Q.; He, K.; Liu, M.*; Zhang, Y.*; Yao, S. A cyclic signal amplification strategy to fluorescence and colorimetric dual-readout assay for the detection of H2O2-relatedanalytes and application to colorimetric logic gate, Sensors and Actuators B, 2018, 260, 908–917.
2017年
1. Wu, Q.; Chen, H.; Fang, A.; Wu, X.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S. A universal multifunctional nanoplatform based on the target-induced in situ promoting Au seeds growth to quench fluorescence of upconversion nanoparticles. ACS Sens., 2017, 2(12), 1805-1813.
2. Zhang, S.; Li, R.; Liu, X.; Yang, L.; Lu, Q.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., A novel multiple signal amplifying immunosensor based on the strategy of in situ-produced electroactive substance by ALP and carbon-based Ag-Au bimetallic as the catalyst and signal enhancer. Biosensors and Bioelectronics 2017, 92, 457-464.
3. Yang, L.; Huang, N.; Huang, L.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., An electrochemical sensor for highly sensitive detection of copper ions based on a new molecular probe Pi-A decorated on graphene. Analytical Methods 2017, 9 (4), 618-624.
4. Fang, A.; Chen, H.; Li, H.; Liu, M.*; Zhang, Y. *; Yao, S., Glutathione regulation-based dual-functional upconversion sensing-platform for acetylcholinesterase activity and cadmium ions. Biosensors and Bioelectronics 2017, 87, 545-551.
5. Chen, Y.; Liu, X.; Zhang, S.; Yang, L.; Liu, M.*; Zhang, Y.; Yao, S., Ultrasensitive and simultaneous detection of hydroquinone, catechol and resorcinol based on the electrochemical co-reduction prepared Au-Pd nanoflower/reduced graphene oxide nanocomposite. Electrochimica Acta 2017, 231,677-685.
2016年
1. Zhang, S.; Liu, X.; Huang, N.; Lu, Q.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., Sensitive detection of hydrogen peroxide and nitrite based on silver/carbon nanocomposite synthesized by carbon dots as reductant via one step method. Electrochimica Acta 2016, 211, 36-43.
2. Zhang, S.; Huang, N.; Lu, Q.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., A double signal electrochemical human immunoglobulin G immunosensor based on gold nanoparticles-polydopamine functionalized reduced graphene oxide as a sensor platform and AgNPs/carbon nanocomposite as signal probe and catalytic substrate. Biosensors and Bioelectronics 2016, 77, 1078-1085.
3. Zhang, L.; Hou, W.; Lu, Q.; Liu, M.*; Chen, C.; Zhang, Y.; Yao, S., Colorimetric detection of hydrogen peroxide and lactate based on the etching of the carbon based Au-Ag bimetallic nanocomposite synthesized by carbon dots as the reductant and stabilizer. Analytica Chimica Acta 2016, 947, 23-31.
4. Yang, L.; Liu, X.; Lu, Q.; Huang, N.; Liu, M.*; Zhang, Y.; Yao, S., Catalytic and peroxidase-like activity of carbon based-AuPd bimetallic nanocomposite produced using carbon dots as the reductant. Analytica Chimica Acta 2016, 930, 23-30.
5. Yang, L.; Huang, N.; Lu, Q.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., A quadruplet electrochemical platform for ultrasensitive and simultaneous detection of ascorbic acid, dopamine, uric acid and acetaminophen based on a ferrocene derivative functional Au NPs/carbon dots nanocomposite and graphene. Analytica Chimica Acta 2016, 903, 69-80.
6. Fang, A.; Wu, Q.; Chen, H.; Li, H.; Liu, M.*; Zhang, Y. *; Yao, S. Upconversion Ratiometric Fluorescence and Colorimetric Dual-Readout Assay for Uric Acid, Biosensors and Bioelectronics 2016, 86, 664-670.
2015年
1. Huang, N.; Zhang, S.; Yang, L.; Liu, M.*;Li, H.; Zhang, Y.; Yao, S., Multifunctional Electrochemical Platforms Based on the Michael Addition/Schiff Base Reaction of Polydopamine Modified Reduced Graphene Oxide: Construction and Application. ACS Applied Materials &Interfaces 2015, 7 (32), 17935-17946.
2. Huang, N.; Liu, M.*; Li, H.; Zhang, Y.; Yao, S., Synergetic signal amplification based on electrochemical reduced graphene oxide-ferrocene derivative hybrid and gold nanoparticles as an ultra- sensitive detection platform for bisphenol A. Analytica Chimica Acta 2015, 853, 249-257.
3. Deng, J.; Lu, Q.; Hou, Y.; Liu, M.*; Li, H.; Zhang, Y.*;Yao, S., Nanosensor Composed of Nitrogen-Doped Carbon Dots and Gold Nanoparticles for Highly Selective Detection of Cysteine with Multiple Signals. Analytical Chemistry 2015, 87 (4), 2195-2203.
4. Huang, N.; Liu, M.*; Deng, J.; Wang, L., Zhang, Y.; Yao, S. Fabrication of New GH-CS/Fc-NH2/Cytc Modified Electrodeand Its Application in Detection of Nitrite, Chinese Journal of Analytical Chemistry, 43( 3), 2015, 325-332.
获奖情况
1.“碳、硅纳米材料及其复合物的合成及分析应用”,湖南省自然科学二等奖(排名第二), 2018年。
2.湖南省自然科学优秀论文一等奖,湖南省科技厅,2015.6。
3.基于新型对亚苯基亚乙炔基衍生物的小分子化学/生物传感研究. 湖南省优秀博士论文奖,2015年。
4.刘美玲. 基于新型对亚苯基亚乙炔基衍生物的小分子化学/生物传感研究. 88805j新莆京优秀博士论文. 2013年.
5.刘美玲. 电化学石英晶体阻抗及现场红外光谱在生物和聚合物系中的应用研究. 湖南省优秀硕士论文奖, 2008年.
6.刘美玲, 张友玉, 谢青季. 石英晶体阻抗和电化学阻抗联用研究单宁与牛血清白蛋白的结合过程并估算其动力学参数. 长沙市自然科学优秀学术论文奖, 一等奖, 2007年.